Tramadol and Hiccups

Since 1993 tramadol (Tramal?, Tramagetic?) is available in the Netherlands and since 2003 tramadol is also available in combination with paracetamol (Zaldiar?). Tramadol is a centrally acting analgesic, which is indicated for acute and chronic pain, such as pain due to surgery or trauma, and malignant diseases. Tramadol is a racemate of two enantiomers. The cis-enantiomer binds to the