Tramadol Description

Tramadol? is a centrally acting analgesic. The chemical name for tramadol hydrochloride is (?)cis-2-[(dimethylamino)methyl]-1-(3-methoxyphenyl cyclohexanol hydrochloride.Tramadol?The molecular weight of tramadol hydrochloride is 299.8. Tramadol hydrochloride is a white, bitter, crystalline and odorless powder. It is readily soluble in water and ethanol and has a pKa of 9.41. The water/n-octanol

Tramadol Compatibility with Drugs

Tramadol hydrochloride is a centrally acting synthetic analgesic with a dual mechanism of action. Tramadol and its Odesmethyl metabolite (M1) bind to opioid receptors, with M1 having a 200-fold higher affinity for binding to these receptors. Tramadol has also been shown to inhibit the uptake of norepinephrine and serotonin, suggesting that its antinociceptive activity is mediated by both opioid

Tramadol and Hiccups

Since 1993 tramadol (Tramal?, Tramagetic?) is available in the Netherlands and since 2003 tramadol is also available in combination with paracetamol (Zaldiar?). Tramadol is a centrally acting analgesic, which is indicated for acute and chronic pain, such as pain due to surgery or trauma, and malignant diseases. Tramadol is a racemate of two enantiomers. The cis-enantiomer binds to the